An example of how this could cause a problem is say if an app added a required file to the hard drive, and performed a check to make sure that file's location was recorded in the registry. Some other registry entries refer to entries elsewhere in the registry, and cleaners will check those as well, making sure they exist. Many of the entries in Windows Registry list files and their location or path on the hard drive - registry cleaners generally look to see if those files are there, and if not, offer to delete that entry. Setting a Restore Point should also work, though sometimes it doesn't. Short of that, there have been good reports regarding Tweakingcom Registry Backup - free with a portable version available.

The safest way to find out for yourself is to do a partition image backup, and give Wise Registry Cleaner Pro a try.

Some people are adamant that the registry be left alone, while some people - too many IMHO to all be shills - report that using a registry cleaner has helped performance with their copy of Windows, sometimes quite a lot. Over the years Microsoft has generally kept silent on registry cleaners, cleaning &/or defragging the registry etc., maintaining instead that Windows should be reinstalled periodically. Customizable Cleanup Options for Advanced Users.System Tune-up Optimizes System Settings for Better Performance.Fix Registry Problems and Boost Your PC Performance.

If you wish, you can also have all problems corrected automatically, all changes to your system are monitored by Wise Registry Cleaner and can be undone with a few mouse clicks, so you can use Wise Registry Cleaner feel relieved. By fixing the obsolete information in Windows registry, your system will can work better and more quickly, after Wise Registry Cleaner analyzes your system for problems, you can individually view each of the problems found and call up a detailed description. It scans the Windows registry and finds incorrect or obsolete information in the registry. It is so easy to use, even the least experienced user can easily repair registry with this tool. Its scanning engine is thorough, safe and fast. Wise Registry Cleaner is one of the safest Registry cleaning tools available in the market today.

Wise registry cleaner portable